Microfluidic Sperm Sorting Chips
FERTILE® provides a better process for sperm washing, swimming and gradient centrifuging, making these processes with less time and stage demanding. It also sorts sperms with best DNA and physiological quality.!
Our Publications
See our latest article published on Human Reproduction Journal!
Molly M. Quinn,Liza Jalalian,Salustiano Ribeiro, Katherine Ona, Utkan Demirci, Marcelle Cedars, and Mitchell P. Rosen
Microfluidic Sorting Selects Sprem for Clinical Use with Reduced DNA Damage Compared to Density Gradient Centrifugation with Swim-Up in Split Semen Samples
Human Reproduction, pp. 1-6, 2018
STUDY QUESTON
Does microfluidic sorting improve the selection of sperm with lower DNA fragmentation over standard densitygradient centrifugation?
SUMMARY ANSWER
Microfluidic sorting of unprocessed semen allows for the selection of clinically usable, highly motile sperm with nearly undetectable levelsof DNA fragmentation.
WHAT IS KNOWN
Microfluidic devices have been explored to sort motile and morphologically normal sperm from a raw sample without centrifugation; however, it is uncertain whether DNA damage is reduced in this process.
Fertile® Technology
FERTILE®, can be used in IVF (In vitro fertilization), IUI (Intra uterine insemination), ICSI (Intracytoplasmic sperm injection).
FERTILE® provides a better process for sperm washing, swimming and gradient centrifuging, making these processes with less time and stage demanding.
It also sorts sperms with best DNA and physiological quality.
Umut GÜRKAN, Ph.D.
Scientific Advisor
Umut A. Gurkan is leading the CASE Biomanufacturing and Microfabrication Laboratory (CASE-BML) at Case Western Reserve University (CWRU).